Folic acid CAS NO.59-30-3 CAS NO.59-30-3

 

Folic acid Chemical Properties

Melting point	250 °C
alpha	20 º (c=1, 0.1N NaOH)
Boiling point	552.35°C (rough estimate)
density	1.4704 (rough estimate)
refractive index	1.6800 (estimate)
storage temp.	2-8°C
solubility	boiling water: soluble1%
form	Crystalline Powder
pka	pKa 2.5 (Uncertain)
color	Yellow to orange
Odor	Odorless
PH Range	4
Water Solubility	1.6 mg/L (25 ºC)
Merck	14,4221
BRN	100781
BCS Class	3
Stability:	Stable. Incompatible with heavy metal ions, strong oxidizing agents, strong reducing agents. Solutions may be light and heat sensitive.
InChIKey	OVBPIULPVIDEAO-LBPRGKRZSA-N
LogP	-0.990 (est)
CAS DataBase Reference	59-30-3(CAS DataBase Reference)
NIST Chemistry Reference	Folic acid(59-30-3)
EPA Substance Registry System	L-Glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- (59-30-3)

Safety Information

Risk Statements	33-62-68
Safety Statements	24/25
WGK Germany	1
RTECS	LP5425000
F	8
TSCA	Yes
HS Code	29362900
Hazardous Substances Data	59-30-3(Hazardous Substances Data)
Toxicity	A water soluble vitamin required in the diet of mammals. Sulfonamide drugs are selectively toxic to bacteria because they inhibit the incorporation of p-aminobenzoic acid into folic acid, a biosynthetic process in bacteria. Folic acid deficiency adversely affects prenatal development in humans. Dietary supplementation with folic acid dramatically reduces the incidence of neural tube defects in humans. Folic acid deficiency may also contribute to the causes of megaloblastic macrocytic anemia and a consequence of this is that this disease can be induced, as a side effect, when methotrexate, a folic acid antagonist, is used in cancer chemotherapy

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